Gastroesophageal Reflux

All babies spit up. That’s just normal. But when your baby spits up all the time, isn’t gaining weight, and seems distressed or always unhappy, trust your feelings and ask your doctor. It may be a sign of something more serious—such as gastroesophageal reflux (GER).

GER occurs when stomach acid regularly gets into your child’s esophagus, causing burning and pain. Studies estimate that up to 40—56% of infants with GER also suffer from cow milk allergy.6

Only your doctor can tell you the best way to treat or manage it.

How Neocate Can Help

If food protein allergies are at work, Neocate is an excellent option for the dietary management of GER. Neocate can play this role because it’s different from other formulas.

Neocate is based on free amino acids, the simple building blocks of protein, which makes it easier for infants and children to digest.  Neocate has neither whole nor fragmented protein chains that can trigger an allergic response. Amino acid formulas, such as Neocate, are the most hypoallergenic formulas available.

Neocate has been clinically proven to help with gastrointestinal conditions in as little as three days1 and improve all other allergy-related conditions such as skin rash, eczema or GER in 14 days.2,3 Neocate provides an adequate source of nutrition and has been seen to promote normal and catch-up growth in infants.4,5

You can find more information on GER in our Food Allergy Living Blog.


1. de Boissieu D et al. Allergy to extensively hydrolyzed cow’s milk proteins in infants: Identification and treatment with an amino acid-based formula. J. Pediatr1997; 131:744-747.

2. Vanderhoof JA et al. Intolerance to protein hydrolysate infant formulas: An underrecognized cause of gastrointestinal symptoms in infants. J. Pediatr1997; 131:741-744.

3. Hill DJ et al. The natural history of intolerance to soy and extensively hydrolyzed formula in infants with multiple food protein intolerance. J. Pediatr1999; 135:118-121.

4. Isolauri E et al. Efficacy and safety of hydrolyzed cow’s milk and amino acid-derived formulas in infants with cow’s milk allergy. J. Pediatr1995; 127:550-557.

5. Niggemann B et al. Prospective, controlled, multi-center study on the effect of an amino acid-based formula in infants with cow’s milk allergy/intolerance and atopic dermatitis. Pediatr Allergy Immunol2001; 12:78-82.

6. Nielsen RG et al. Severe gastroesophageal reflux disease and cow milk hypersensitivity in infants and children: Disease association and evaluation of a new challenge procedure. J Pediatr Gastroenterol Nutr. 2004; 39:383–391