Eosinophilic Esophagitis Diet & Management


Try the Six Food Elimination Diet for EoE


There is currently no cure for EoE. However, there are ways to manage it, alone or in combination. Talk with your healthcare team about which may work well for you. Please remember, nutritional therapy must be under the direction and supervision of a healthcare professional.



Managing EoE through diet can be an effective way to relieve symptoms and prevent further damage to the esophagus. In EoE, with nutrition management, you can find out which foods are triggering EoE and remove them. This strategy involves avoiding food allergens, and there are several ways to go about it.

Amino Acid-Based, or Elemental, Diet

All sources of whole proteins are removed from the diet. This involves the use of an amino acid-based formula, such as Neocate, which has neither whole nor fragmented protein chains that can trigger an allergic response.

Simple sugars, salt, and oils may be permitted (100% apple juice, white grape juice, and sugar). Check with your healthcare professional if this is appropriate for you or your child. Formulas such as Neocate may be given either by mouth or tube-feeding, depending on your child’s nutritional needs. Neocate® Nutra is a semi-solid that can also be used to supplement the diet from 6 months of age.

In general, amino acid-based diets are successful in relieving symptoms and lowering eosinophils in the esophagus for about 95% of children.

Elimination Diet

This approach may remove common food allergens (see the Six Food Elimination Diet) or it might remove foods based on positive allergy tests often seen in children. In general, elimination diets are successful in relieving symptoms and lowering eosinophils in the esophagus for about 75% of children.

If your child’s symptoms and/or biopsy eosinophil count responds to an amino acid-based or elimination diet, the next step would be to reintroduce foods. By adding back one food at a time over a period of weeks, you can find out which foods are causing a reaction. A child who has been on an amino acid-based formula only may take months to return to a typical diet. During this time, the amino acid-based formula will help ensure your child’s nutritional needs (vitamins, minerals, and calories) are being met. Good nutrition is key to support normal growth and development.

Combination of the Two

Amino acid-based products (Neocate Splash, Neocate Junior or Neocate Syneo Infant) can be recommended by your doctor to supplement an elimination diet for EoE. Neocate is nutritionally complete and adding it to the elimination diet can help better meet your or your child's nutritional needs and support growth.



Corticosteroids and PPI-type medications can be successful in relieving symptoms and reducing the eosinophil load in EoE. Unlike dietary management, medications will not uncover which foods trigger EoE. While medication can improve symptoms, they can recur once medications are stopped if the trigger foods are still being eaten.

Systemic Steroids

These are steroids taken by mouth that spread throughout the body. They are often only used short-term and may be reserved for patients with severe symptoms. This type of steroid may have side effects, especially with long-term use.

Topical, Swallowed Steroids

This approach involves swallowing a small amount of steroid that's targeted at the esophagus. The topical/swallowed steroid is often thickened with Neocate Nutra, other powders or thick liquids.

Proton Pump Inhibitors

PPI drugs such as omeprazole and esomeprazole decrease the amount of acid produced in the stomach. However, doctors aren’t sure why they sometimes work for EoE.

How Neocate Can Help

How Neocate Can Help

Neocate offers a variety of products that can be helpful for children and adults with EoE. Ask your healthcare professional about nutritionally complete Neocate Splash, which provides the nutrition your child needs in a variety of tasty flavors and in convenient, ready-to-go, drink boxes. In addition, Neocate Junior offers a powdered variety of flavors, with prebiotics. It is also available without. Nutra can also be used to supplement the diets of children (above the age of 6 months) with EoE experiencing feeding difficulties. Because of its spoonable consistency, it is a great tool for adding texture and variety to the diet. More information on EoE can be found in our EoE caregiver guide.

A Guide to Successfully Managing Eosinophilic Esophagitis

WATCH THE VIDEO: A Guide to Successfully Managing Eosinophilic Esophagitis

Eosinophilic Esophagitis Products

Talk to your healthcare provider to determine which Neocate products are right for you.

Further Resources

The content you are trying to access is intended for healthcare professionals only.

Are you a healthcare professional?