Amino acid-based formulas do not contain any intact protein chains and are made from the building blocks of protein, called amino acids.

• The protein source in the formula is 100% free amino acids.
• There are no intact proteins or even small protein fragments (peptides) that can cause an allergic reaction.
• The hypoallergenicity of Neocate was first established in 1992, according to the guidelines set out by the AAP. Neocate Syneo Infant is also hypoallergenic according to the same guidelines.

Freshly prepared Neocate Syneo Infant is best. Formula prepared in advance should be cooled rapidly, stored in the refrigerator at 35-40℉ (2-4℃) and used within 24 hours of preparation. Neocate Syneo Infant formula remaining in the bottle after one hour of feeding should be discarded.

Yes, although we recommend doing so carefully. Too high of a temperature (above 104℉, or 40℃) may lessen the benefits of the probiotic cultures. If you choose to warm Neocate Syneo Infant, we recommend against using a microwave, as we do for all of our formulas, due to the risk of hot spots and burns. Instead, gently warm cold formula using a bottle warmer, a warm water bath, or by holding the bottle under warm, running water. We suggest using a thermometer to ensure the temperature does not exceed 104℉ (40℃).

Sealed cans of Neocate Syneo Infant should be stored in a cool, dry place and used by the expiration date, which is located on the bottom of each can. We recommend that, after the can is opened, it should be used within 2 weeks. This is because having the can of Neocate Syneo Infant open for more than 2 weeks, even with the lid on, may lessen the benefits of the probiotic cultures.

If your healthcare professional has recommended Neocate Syneo Infant and you're ready to switch your baby from another formula or breast milk you might prefer to transition gradually over the course of a few bottles or a few days. This way your baby will be less likely to notice any differences.

Infants usually adjust to a hypoallergenic formula and settle into a routine after a few days or weeks. The same may be true when adding prebiotics and/or probiotics to the diet—a gradual transition may help.

The research behind Neocate Syneo Infant suggests that there may be some initial changes in stool characteristics (e.g., color and consistency) during the early transition to this product from a formula without pre- and probiotics. Stools may be softer, more like breastfed infants. In the first days/weeks of use, your baby may also have more gas or flatulence, which may cause some temporary discomfort or fussiness. Talk to your baby's doctor or other healthcare professional about the need to transition gradually onto Neocate Syneo Infant.

When a baby is on Neocate, the first stools tend to be green and can be dark - a lot of parents describe the color as hunter green (but contact your baby's doctor if the stool looks black, which could be blood in the stool). Green is completely normal (Green is Glorious!) and is due to the special composition of Neocate and the way it is digested and absorbed in the body.

For most babies on Neocate, the green color will last for at least the first few days. It may fade after several weeks, but for some little ones stools will be green as long as they're on Neocate. Often stools will change to a yellow/tan/khaki color if the green fades. This is normal, and is a result of the body adjusting to the way Neocate is digested and absorbed. Color can also change when solid foods are introduced into the diet.

The consistency of stools for babies on Neocate tends to be soft and somewhat pasty, though this can vary. For some babies the stools will be looser, and for others more solid or formed. Again, adding solid foods to the diet can affect consistency. Mucus in the stool is not typical so if you see this, you should let the physician know.

Neocate Syneo Infant is a specially formulated medical food and should only be used under medical supervision.

Neocate Syneo Infant can be given through gastric feeding tubes that empty into the stomach. Routine nutrient monitoring recommendation in line with guidance statement. Ask your healthcare professional if you have further questions. Neocate Syneo Infant is a specially formulated medical food and should only be used under medical supervision.

Neocate Syneo Infant is not recommended for use in short bowel syndrome patients unless a risk and benefit analysis is completed by a healthcare professional and the infant is monitored. Ask your healthcare professional if you have further questions. Neocate Syneo Infant is a specially formulated medical food and should only be used under medical supervision.

Neocate^® Syneo^® Infant has been certified Kosher Pareve Non-Passover. Check out our blog on the Kosher status of Neocate products to learn more about the formula and the kosher certification process.