This site is for HCPs only
Take a 3 minute journey through the
allergic infant gut with Dr. Benjamin Gold

The human body is home to trillions of microbes, mostly bacteria which outnumber cells in the human body by up to 10 times. These resident microbes are known as “gut microbiota” and work together with the body to form a “super organism”.

The development of a healthy, balanced gut microbiota in infancy is a critical time period in early life.

In this video you will discover more about
gut microbiota dysbiosis in allergic infants

A unique blend of pre- and probiotics has been shown
to help balance the gut microbiota of allergic infants

In a multicenter, prospective, randomized, double-blind controlled study in cow milk-allergic infants:
Neocate Syneo Infant helps balance the gut microbiota to be closer to that of healthy, breastfed infants.*1,2

Results:
Higher levels of fecal bifidobacteria and lower levels of fecal clostridia + eubacteria were observed with Neocate Syneo Infant, bringing the gut microbiota closer to that of healthy breastfed infants* (vs. a standard AAF without the Syneo blend (p<0.001))*1,2

When you look beyond allergic symptom resolution,
you discover that you can do more

Neocate® Syneo™ Infant

The first and only hypoallergenic formula with
prebiotics and probiotics, specifically designed
for food-allergic infants

  • Effectively resolves food allergy symptoms3
  • Supports growth & development3,4
  • Helps balance the gut microbiota of food-allergic infants
    to be closer to that of healthy, breastfed infants*1,2

Nutritionally complete, amino acid-based formula for babies 0-12 months

Neocate Syneo Infant is backed by 3 clinical studies in infants.1,3,4 Two of these studies demonstrate that Neocate Syneo Infant is well tolerated and supports normal growth.3,4 The third study demonstrates that Neocate Syneo Infant helps balance the gut microbiota of food-allergic infants to be closer to that of healthy, breastfed infants.*1,2 Neocate Syneo Infant has been shown to be hypoallergenic based on criteria developed by the American Academy of Pediatrics (AAP) subcommittee on Nutrition and Allergic Diseases.4 Neocate Syneo Infant is made in the same dedicated, 100% dairy protein-free environment as our other Neocate powdered products.

Who is this formula for?

Neocate Syneo Infant is specially formulated for the dietary management of infants with cow milk allergy (CMA), multiple food
allergies (MFA) and related GI and allergic conditions, including food protein-induced enterocolitis syndrome (FPIES), eosinophilic
esophagitis (EoE) and gastroesophageal reflux (GER).

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References
  1. Michaelis LJ, et al. An amino acid-based formula with synbiotics affects faecal microbiota in non-IgE mediated cow’s milk allergic infants. at EAACI Annual Meeting. Allergy. 2016;71(S102):58(114).
  2. Candy DCA, et al. Dietary management of non-IgE mediated cow's milk allergic infants with a synbiotics-supplemented amino acid-based formula: effects on faecal microbiota and clinical symptoms. Poster at WCPGHAN Meeting. 2016.
  3. Burks AW, et al. Synbiotics-supplemented amino acid-based formula supports adequate growth in cow's milk allergic infants. Pediatr Allergy Immunol. 2015;26:316-22.
  4. Harvey BM, et al. Effects on growth and tolerance and hypoallergenicity of an amino acid-based formula with synbiotics. Pediatr Res. 2014;75:343-51.

* Infants after 8 weeks of management with standard amino acid-based formula (control) or amino acid-based formula with pre- and probiotics (test) compared to age-matched, healthy, breastfed infants. At 8 weeks, levels of both bifidobacteria and Eubacterium rectale + Clostridium coccoides group were measured as a percentage of total fecal bacteria. Test group median levels were different than control group (p<0.001), and were closer to breastfed infant levels vs. control group.

✝ Statistics are based on ANCOVA comparing test vs. control with Week 8 values as outcome, stratification factor (skin or gastrointestinal symptoms) and imputed baseline values as covariate and treatment as fixed effect. The grey shaded area represents the sample 25th to 75th percentile of the reference group (healthy subjects) and the grey horizontal lines represent the minimum and maximum values of this reference group. The bottom and top edges of the box are located at the sample 25th and 75th percentiles. The center horizontal line is drawn at the 50th percentile (median). The whiskers of the box plots show the minimum and maximum values.

‡ AAF = Amino acid-based formula